ABRUPT CLINE FOR SEX CHROMOSOMES IN A HYBRID ZONE BETWEEN TWO SPECIES OF MICE
ABRUPT CLINE FOR SEX CHROMOSOMES IN A HYBRID ZONE BETWEEN TWO SPECIES OF MICE
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DOI：
10.1111/j.1558-5646.1992.tb00625.x
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发表时间：
1992-08
期刊：
影响因子：
3.3
通讯作者：
P. Tucker;R. Sage;J. Warner;A. Wilson;E. Eicher
中科院分区：
文献类型：
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作者：
P. Tucker;R. Sage;J. Warner;A. Wilson;E. Eicher
我们比较了沿沿着160 km的横带，在M. Acetylticus和M.在德国南部和奥地利西部的小家鼠使用7个遗传标记。其中包括一个Y特异性DNA序列（YB 10）、两个X特异性基因座（DXWas 68和DXWas 31）和四个常染色体同工酶基因座（Es-10、Es-1、Mpi-1和Np-1）。随机效应逻辑回归分析使我们能够检查M。从混合区的西部边缘的等位基因频率和地理距离，并允许在基因座之间的渐变群中点和宽度的差异进行统计评估。与四个常染色体标记中的三个相比，观察到所有三个性染色体标记在整个区域的移动更有限。如果差异运动反映了杂种背景上特定等位基因（或紧密连锁基因座上的等位基因）的适合度差异，那么在杂种区中移动到有限程度的等位基因可能有助于两个物种之间的杂种崩溃。X和Y特异性等位基因的有限流动表明性染色体在小鼠物种形成中发挥了重要作用。
We compared the patterns of movement of sex chromosomal and autosomal loci along a 160 km transect across a zone of hybridization between M. domesticus and M. musculus in southern Germany and western Austria using seven genetic markers. These included one Y‐specific DNA sequence (YB10), two X‐specific loci (DXWas68 and DXWas31), and four autosomal isozyme loci (Es‐10, Es‐1, Mpi‐1, and Np‐1). Random effects logistic regression analysis enabled us to examine the relationship between M. domesticus allele frequency and geographic distance from the western edge of the hybrid zone and allowed statistical evaluation of differences in cline midpoint and width among loci. More limited movement was observed for all three sex chromosomal markers across the zone compared with three of the four autosomal markers. If differential movement reflects fitness differences of specific alleles (or alleles at closely linked loci) on a hybrid background, then alleles that move to a limited extent across a hybrid zone may contribute to hybrid breakdown between two species. The limited flow of both X‐ and Y‐specific alleles suggest that sex chromosomes have played an important role in Mus speciation.