Unenhanced Dynamic MR Angiography: High Spatial and Temporal Resolution by Using True FISP-based Spin Tagging with Alternating Radiofrequency
Unenhanced Dynamic MR Angiography: High Spatial and Temporal Resolution by Using True FISP-based Spin Tagging with Alternating Radiofrequency
复制标题
非增强型动态 MR 血管造影：通过使用真正的基于 FISP 的自旋标记和交替射频实现高空间和时间分辨率
DOI：
10.1148/radiol.10091543
复制
发表时间：
2010-07-01
期刊：
影响因子：
19.7
通讯作者：
Wang, Danny J. J.
中科院分区：
文献类型：
--
作者：
Yan, Lirong;Wang, Sumei;Wang, Danny J. J.
目的：介绍一种未增强的四维时间分辨动态磁共振（MR）血管造影技术，采用稳态进动自旋标记交替射频（星星），也称为True星星。材料和方法：本研究获得了机构审查委员会的批准，符合HIPAA。获得所有研究受试者的知情同意书。在8名健康志愿者中，TrueSTAR技术的空间和时间分辨率进行了优化。在另外6名健康志愿者中，通过Wilcoxon符号秩检验，将TrueSTAR动态MR血管造影图像的对比噪声比（CNR）和信噪比（SNR）与使用标准Look-Echo-Planar技术获得的图像进行比较。最后，一例动静脉畸形（AVM）的患者进行了研究，通过使用这种technique.Results：的TrueSTAR动态磁共振血管造影图像的SNR和CNR分别高出29%和39%，分别与那些通过使用标准的Look-Scan回波平面成像序列（均P = 0.028）。在AVM患者，TrueSTAR动态MR血管造影描绘了标记的血液通过供血动脉流入病灶和drainingvein.Conclusion的动态过程：结果表明，TrueSTAR是一种很有前途的非增强动态MR血管造影技术的脑血管疾病，如AVM，狭窄闭塞性疾病，动脉瘤的临床评价。
Purpose: To present an unenhanced four-dimensional time-resolved dynamic magnetic resonance (MR) angiography technique with true fast imaging with steady-state precession-based spin tagging with alternating radiofrequency (STAR), also called TrueSTAR.Materials and Methods: This study received Institutional Review Board approval and was HIPAA compliant. Informed consent was obtained from all study subjects. In eight healthy volunteers, the spatial and temporal resolution of the TrueSTAR technique were optimized. In another six healthy volunteers, the contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) of the TrueSTAR dynamic MR angiography images were compared with those acquired by using a standard Look-Locker echo-planar technique by using the Wilcoxon signed rank test. Finally, one patient with an arteriovenous malformation (AVM) was studied by using this technique.Results: The SNR and CNR of the TrueSTAR dynamic MR angiography images were 29% and 39% higher, respectively, compared with those acquired by using a standard Look-Locker echo-planar imaging sequence (both P = .028). In the AVM patient, TrueSTAR dynamic MR angiography delineated the dynamic course of labeled blood flowing through feeding arteries into the nidus and draining veins.Conclusion: The results suggest that TrueSTAR is a promising unenhanced dynamic MR angiography technique for clinical evaluation of cerebrovascular disorders such as AVM, steno-occlusive disease, and aneurysm.