Oblique incidence reflectometry: optical models and measurements using a side-viewing gradient index lens-based endoscopic imaging system.
Oblique incidence reflectometry: optical models and measurements using a side-viewing gradient index lens-based endoscopic imaging system.
复制标题
斜入射反射测量：使用基于侧视梯度折射率透镜的内窥镜成像系统的光学模型和测量。
DOI：
10.1117/1.jbo.19.6.067002
复制
发表时间：
2014
影响因子：
3.5
通讯作者：
Barton,JenniferK
中科院分区：
文献类型：
--
作者：
Wall,RAndrew;Barton,JenniferK
A side-viewing, 2.3-mm diameter oblique incidence reflectometry endoscope has been designed to obtain optical property measurements of turbid samples. Light from a single-mode fiber is relayed obliquely onto the tissue with a gradient index lens-based distal optics assembly and the resulting diffuse reflectance profile is imaged and collected with a 30,000 element, 0.72 mm clear aperture fiber bundle. Sampling the diffuse reflectance in two-dimensions allows for fitting of the reflected intensity profile to a well-known theoretical model, permitting the extraction of both absorption and reduced scattering coefficients of the tissue sample. Models and measurements of the endoscopic imaging system are presented in tissue phantoms andin vivomouse colon, verifying the endoscope’s capabilities to accurately measure effective attenuation coefficient and differentiate diseased from normal colon.
