REGULATION OF PROGRESSION THROUGH THE G1 PHASE OF THE CELL-CYCLE BY THE RUM1(+) GENE

REGULATION OF PROGRESSION THROUGH THE G1 PHASE OF THE CELL-CYCLE BY THE RUM1(+) GENE
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DOI:
10.1038/367236a0
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发表时间:
1994-01-20
期刊:
影响因子:
64.8
通讯作者:
NURSE, P
NURSE, P
中科院分区:
综合性期刊1区
文献类型:
--
作者:
MORENO, S;NURSE, P

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Rum1+基因被鉴定为裂殖酵母中G1期进展的新调节因子。它影响G1期调控的三个方面:G1期长度的确定,有丝分裂完成后S期的依赖性,以及G1期结束前有丝分裂的抑制。我们认为它在调节细胞周期的G1期中具有核心作用。
The rum1+ gene is identified as a new regulator of G1 progression in fission yeast. It influences three aspects of G1 regulation: determination of the length of G1, dependence of S phase upon completion of mitosis, and restraint of mitosis until G1 is finished. We propose that it has a central role in regulating the G1 phase of the cell cycle.