Residual lifetime risk of fractures in women and men
Residual lifetime risk of fractures in women and men
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DOI：
10.1359/jbmr.070315
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发表时间：
2007-06-01
影响因子：
6.2
通讯作者：
Nguyen, Tuan V.
中科院分区：
文献类型：
--
作者：
Nguyen, Nguyen D.;Ahlborg, Henrik G.;Nguyen, Tuan V.
在1358名女性和858名男性的样本中，年龄≥ 60岁，随访时间长达15年，据估计，女性骨折死亡率调整的剩余寿命风险为44%，男性为25%。在1989年来自杜博骨质疏松流行病学研究的白色背景的BMD T评分≥ 60岁的患者中进行分析。参与者被跟踪长达15年。在随访期间，低创伤，非病理性骨折的发生率，通过X线和个人访谈证实，记录。还记录了死亡率。在基线时通过DXA（GE-LUNAR）测量股骨颈BMD。从60岁的骨折的剩余寿命风险估计的生存分析，考虑到死亡的竞争风险。结果：调整后的竞争风险的死亡，RLRF为女性和男性从60岁分别为44%（95%CI，40-48）和25%（95%CI，19-31），分别。对于骨质疏松症患者（BMD T评分
In a sample of 1358 women and 858 men, >= 60 yr of age who have been followed-up for up to 15 yr, it was estimated that the mortality-adjusted residual lifetime risk of fracture was 44 % for women and 25 % for men. Among those with BMD T-scores = 60 yr of age as of 1989 of white background from the Dubbo Osteoporosis Epidemiology Study were analyzed. The participants have been followed for up to 15 yr. During the follow-up period, incidence of low-trauma, nonpathological fractures, confirmed by X-ray and personal interview, were recorded. Incidence of mortality was also recorded. BMD at the femoral neck was measured by DXA (GE-LUNAR) at baseline. Residual lifetime risk of fracture from the age of 60 was estimated by the survival analysis taking into account the competing risk of death.Results: After adjusting for competing risk of death, the RLRF for women and men from age 60 was 44% (95% CI, 40-48) and 25% (95% CI, 19-31), respectively. For individuals with osteoporosis (BMD T-scores