Antigen-processing and presentation pathways select antigenic HIV peptides in the fight against viral evolution.
Antigen-processing and presentation pathways select antigenic HIV peptides in the fight against viral evolution.
复制标题
抗原加工和呈递途径选择抗原性 HIV 肽来对抗病毒进化。
DOI：
10.1038/ni0609-566
复制
发表时间：
2009
影响因子：
30.5
通讯作者：
Margulies,DavidH
中科院分区：
文献类型：
--
作者：
Margulies,DavidH
The evolution of immunodominant epitopes in HIV-1 Gag proteins correlates with quantitative measures of several antigen processing events. Thus, peptides recognized by CD8+cytolytic T cells are selected by their ability to pass through the antigen processing pathway, as well as by their binding to HLA molecules.
