Trajectories of Physical Function Decline and Psychological Functioning: The Quebec Longitudinal Study on Nutrition and Successful Aging (NuAge)
Trajectories of Physical Function Decline and Psychological Functioning: The Quebec Longitudinal Study on Nutrition and Successful Aging (NuAge)
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DOI：
10.1093/geronb/gbq085
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发表时间：
2011-07-01
影响因子：
6.2
通讯作者：
Gray-Donald, Katherine
中科院分区：
文献类型：
--
作者：
Payette, Helene;Gueye, N'Deye Rokhaya;Gray-Donald, Katherine
背景。随着年龄的增长，身体机能的衰退与严重的健康后果有关。生理和心理功能是有联系的，但这种联系的时间性质尚不清楚。在营养与成功衰老的纵向研究（NuAge; Quebec, Canada）中，使用了来自68-82岁的男性和女性（n = 1,741）的三年随访数据。在认知和抑郁的条件下，使用生长曲线模型来检查全球身体表现得分随时间的轨迹。身体功能明显下降（p < 0.0001）。年龄较大的参与者（50 - 77岁；年龄(2):p < 0.01）的身体机能得分下降速度加快，但不受认知能力和抑郁程度轻微下降的影响。然而，认知水平较低和抑郁症状较多的人在整个随访期间表现出较低的身体能力（p < 0.0001）。身体机能在三年内明显下降，尤其是在最老的一组。心理健康的轻微下降与身体机能的下降并行，但并没有加速它。
Background. Decline of physical function with age is associated with substantial health consequences. Physical and psychological functioning is linked, but the temporal nature of this association remains unclear.Methods. Three-year follow-up data from men and women (n = 1,741), aged 68-82 years, in the longitudinal study on nutrition and successful aging (NuAge; Quebec, Canada) were used. Growth curve modeling was performed to examine trajectories of a global physical performance score across time as conditioned by cognition and depression.Results. Significant decline in physical function was observed (p < .0001). Rate of decline in physical performance score was accelerated in the older participants (>77 years; age(2): p < .01) but not affected by slight decline in cognition or depression. Yet, people with lower cognition level and more depressive symptoms show lower physical capacity throughout the entire follow-up period (p < .0001).Conclusions. Physical function significantly declined over 3 years, in particular in the oldest group. A subtle decline in psychological health paralleled decline in physical function but did not accelerate it.