Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum
Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum
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DOI:
10.1086/302553
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发表时间:
1999-09-01
影响因子:
9.8
通讯作者:
Frebourg, T
中科院分区:
文献类型:
--
作者:
Campion, D;Dumanchin, C;Frebourg, T
To determine the prevalence of early-onset Alzheimer disease (EOAD) and of autosomal dominant forms of EOAD (ADEOAD), we performed a population-based study in the city of Rouen (426,710 residents). EOAD was defined as onset of disease at age