Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum

Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum
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DOI:
10.1086/302553
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发表时间:
1999-09-01
影响因子:
9.8
通讯作者:
Frebourg, T
Frebourg, T
中科院分区:
生物学1区
文献类型:
--
作者:
Campion, D;Dumanchin, C;Frebourg, T

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为了确定早发性阿尔茨海默病(EOAD)和常染色体显性形式的EOAD(ADEOAD)的患病率,我们在鲁昂市(426,710名居民)进行了一项基于人群的研究。EOAD定义为发病年龄
To determine the prevalence of early-onset Alzheimer disease (EOAD) and of autosomal dominant forms of EOAD (ADEOAD), we performed a population-based study in the city of Rouen (426,710 residents). EOAD was defined as onset of disease at age