Hydatiform mole with coexisting live fetus in dichorionic twin gestation
Hydatiform mole with coexisting live fetus in dichorionic twin gestation
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DOI：
10.1016/s0301-2115(00)00338-9
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发表时间：
2001-02-01
影响因子：
2.6
通讯作者：
Sharma, MC
中科院分区：
文献类型：
--
作者：
Malhotra, N;Deka, D;Sharma, MC
一名 29 岁的女性在 12 周时通过常规超声检查诊断出双绒毛膜双胎妊娠。随后 16 周时持续阴道出血的超声检查显示，两个孕囊中有臼齿胎盘和可存活的胎儿。患者拒绝任何侵入性产前检测来确认胎儿的核型。妊娠顺利进行至 21 周。当她自然流产双胞胎胎儿并且胎盘与附着的臼齿组织分离时。脐带血样本的最终核型证实两个胎儿均为 46XY 和 46XX。磨牙组织的组织病理学报告显示完全蜕皮，随后的 DNA Row 细胞计数显示二倍体染色体模式。临床。超声波和染色体检查表明，布伦是四胞胎妊娠，其中两个胚胎发育为正常胎儿，另外两个胚胎退化为完全痣。 (C) 2001 Elsevier Science Ireland Ltd. 保留所有权利。
A case of dichorionic twin pregnancy was diagnosed in a 29-year-old, on routine ultrasound at 12 weeks. Subsequent ultrasounds for persistent vaginal bleeding at 16 weeks revealed molar placenta with viable fetus in both gestational sacs. The patient declined any invasive prenatal testing to confirm the karyotype of the fetus. The pregnancy was managed expectantly until 21 weeks. when she had a spontaneous abortion of twin fetuses and separate placentae with attached molar tissue. A fnal karyotype on cord blood samples confirmed 46XY and 46XX for both fetuses. Histopathology of molar tissue reported complete molt, with diploid chromosomal pattern on subsequent DNA Row cytometry. The clinical. ultrasound and chromosomal examination suggest that there has bren a quadruplet pregnancy where two embryos developed into normal fetuses and other two degenerated to complete moles. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.