Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy (2016 Revision)

Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy (2016 Revision)
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DOI:
10.1016/j.ophtha.2016.01.058
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发表时间:
2016-06-01
期刊:
影响因子:
13.7
通讯作者:
Mieler, William F.
Mieler, William F.
中科院分区:
医学1区
文献类型:
--
作者:
Marmor, Michael F.;Kellner, Ulrich;Mieler, William F.

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背景:美国眼科学会关于氯喹(CQ)和羟氯喹(HCQ)视网膜病变筛查的建议根据有关毒性患病率、危险因素、眼底分布和筛查工具有效性的新信息进行了修订。视网膜病变的模式:虽然许多眼睛的毒性损害部位是黄斑旁的黄斑旁损害,但亚洲患者经常表现出黄斑区外的损害模式。Dose:我们建议每天最多使用HCQ
Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage.Dose: We recommend a maximum daily HCQ use of