Identification of an extracellular bacterial flavoenzyme that can prevent re-polymerisation of lignin fragments.
Identification of an extracellular bacterial flavoenzyme that can prevent re-polymerisation of lignin fragments.
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DOI：
10.1016/j.bbrc.2016.10.144
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发表时间：
2017
影响因子：
3.1
通讯作者：
Rahman Rahmanpour;Lloyd King;T. Bugg
中科院分区：
文献类型：
--
作者：
Rahman Rahmanpour;Lloyd King;T. Bugg
木质素氧化分解的一个重要问题是酚自由基片段重新聚合形成较高分子量物质的趋势。在本文中，我们从Thermobifida fusca中鉴定出一种细胞外黄素依赖性脱氢硫辛酰胺脱氢酶，它可以防止二聚木质素模型化合物的氧化二聚化，该酶可以用作木质素解聚的辅助酶。
A significant problem in the oxidative breakdown of lignin is the tendency of phenolic radical fragments to re-polymerise to form higher molecular weight species. In this paper we identify an extracellular flavin-dependent dehydrolipoamide dehydrogenase fromThermobifida fuscathat prevents oxidative dimerization of a dimeric lignin model compound, which could be used as an accessory enzyme for lignin depolymerisation.