Neutrophil, Platelets, and Eosinophil to Lymphocyte Ratios Predict Gleason Score Upgrading in Low-Risk Prostate Cancer Patients
Neutrophil, Platelets, and Eosinophil to Lymphocyte Ratios Predict Gleason Score Upgrading in Low-Risk Prostate Cancer Patients
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DOI：
10.1159/000494259
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发表时间：
2019-01-01
影响因子：
1.6
通讯作者：
de Cobelli, Ottavio
中科院分区：
文献类型：
--
作者：
Ferro, Matteo;Musi, Gennaro;de Cobelli, Ottavio
背景：一些生化和临床指标已被提出用于选择患者进行主动监测（AS）。然而，其中一些是昂贵的，不容易获得。此外，目前约30%的AS患者患有侵袭性疾病。因此，迫切需要其他工具来准确识别低风险前列腺癌（PCa）患者。患者：我们回顾性分析了260例接受根治性前列腺切除术的患者的病历，根据以下标准符合AS的资格：临床分期T2a或更低，前列腺特异性抗原水平
Background: Several biochemical and clinical markers have been proposed for selecting patients for active surveillance (AS). However, some of these are expensive and not easily accessible. Moreover, currently about 30% of patients on AS harbor aggressive disease. Hence, there is an urgent need for other tools to accurately identify patients with low-risk prostate cancer (PCa). Patients: We retrospectively reviewed the medical records of 260 patients who underwent radical prostatectonny and were eligible for AS according to the following criteria: clinical stage T2a or less, prostate-specific antigen level