A study of the test-retest reliability of ten olfactory tests
A study of the test-retest reliability of ten olfactory tests
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DOI：
10.1093/chemse/20.6.645
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发表时间：
1995-12-01
期刊：
影响因子：
3.5
通讯作者：
Shaman, P
中科院分区：
文献类型：
--
作者：
Doty, RL;McKeown, DA;Shaman, P
对57名年龄从18岁到83岁的受试者在两次测试中进行了10项嗅觉功能测试(包括气味识别、检测、辨别、记忆、阈值上气味强度和愉悦感觉的测试)。平均测试分数的稳定性是在这10项测试的14项测试和日本T&T嗅觉阈值测试的子组件的两个测试阶段确定的。此外，还建立了各测验的重测信度(Pearson R)。除了反应偏差测量外，两个测试阶段的平均测试分数没有显著差异。从统计上看，主要测试措施的可靠性系数分为三类，r值如下：0.43-0.53；0.67-0.71；0.76-0.90。检测阈值比识别阈值更可靠；基于单个递增演示序列的检测阈值比基于楼梯程序的检测阈值可靠得多。对几个测试的测试长度和可靠性之间的关系进行了检验，并建立了数学模型。例如，在含有气味苯乙醇的楼梯系列中，可靠性(R(2)=0.984)与根据斯皮尔曼-布朗公式导出的函数在阈值估计中包含的逆转次数有关；即可靠性=0.455*#逆转/[1+0.455(#逆转-1)]。反转位置本身对可靠性几乎没有影响。总体而言，这项研究表明：(I)嗅觉测试的可靠性存在相当大的差异，(Ii)可靠性是测试长度的函数，以及(Iii)在应用环境中比较名义上不同的嗅觉测试的结果时需要谨慎，因为在某些情况下，结果可能只是反映了测试的不同可靠性。
Ten tests of olfactory function (including tests of odor identification, detection, discrimination, memory, and suprathreshold odor intensity and pleasantness perception) were administered on two test occasions to 57 subjects ranging in age from 18 to 83 years. The stability of the average test scores was determined across the two test sessions for 14 measures derived from these 10 tests and for subcomponents of the Japanese T&T olfactometer threshold test. In addition, the test-retest reliability (Pearson r) of each test measure was established. With the exception of a response bias measure, the average test scores did not differ significantly across the two test sessions. Statistically, the reliability coefficients of the primary test measures fell into three general classes bound by the following r values: 0.43-0.53; 0.67-0.71; 0.76-0.90. Detection threshold values were more reliable than recognition threshold values; those based upon a single ascending presentation series were much less reliable than those based upon a staircase procedure. The relationship between test length and reliability was examined for several of the tests and mathematically modeled. For example, within the staircase series incorporating the odorant phenyl ethyl alcohol, reliability was related (R(2) = 0.984) to the number of reversals included in the threshold estimate by a function derived from the Spearman-Brown formula; namely, reliability = 0.455* # reversals/[1 + 0.455 (# reversals - 1)]. Reversal location, per se, had little influence on reliability. Overall, this study suggests that (i) considerable variation is present in the reliability of olfactory tests, (ii) reliability is a function of test length, and (iii) caution is warranted in comparing results from nominally different olfactory tests in applied settings since the findings may, in some instances, simply reflect the differential reliability of the tests.