Temperature related genetic divergence in Drosophila body size.
Temperature related genetic divergence in Drosophila body size.
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果蝇体型大小与温度相关的遗传差异。
DOI：
10.1093/oxfordjournals.jhered.a108523
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发表时间：
1974
期刊：
影响因子：
--
通讯作者：
J. Powell
中科院分区：
文献类型：
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作者：
J. Powell
米利奇维尔蒙古人种中描述的蒙古性类型是由于独立的21号染色体，加上一个2\q，21<7接合体，该接合体是通过将准完整21的长臂与失去着丝粒但保留卫星的21的长臂结合而产生的。该接合体属于一组罕见的 2\q, 2\q 相互易位结构，其中不同数量的两条染色体 21 以 p ab ab 的非卫星序列或以 Milledgeville 案例中存在的 p ab ba 顺序连接。在 p ab ba 型中，在某些患者的某些染色体扩散中可能观察到双末端随体。在其他所谓的 p a ba 患者中，从未见过卫星。除了 Milledgeville 病例外，许多作者独立报道了串联排列的双卫星 2lq/2\q 易位病例。接合体中存在的 q 片段数量的变化可能在很大程度上解释了这些蒙古人种患者的身体和精神偏离具有三个独立 21 号染色体的蒙古人种典型特征的通常范围。
The type of mongolism described in the Milledgeville mongoloid is due to an independent chromosome 21, plus a 2\q, 21< 7 zygosome produced by uniting the long arms of a quasi complete 21 with the long arms of a 21 that has lost its centromere but retained its satellites. This zygosome belongs to a rare group of 2\q, 2\q reciprocal translocation structures in which various amounts of the two chromosomes 21 join in either the nonsatellited sequence of p ab ab or in the p ab ba order present in the Milledgeville case. In the p ab ba type, biterminal satellites may be observed in some chromosome spreads of some patients. In other supposed p ab ba patients, satellites have never been seen. Aside from the Milledgeville case, a number of authors have independently reported a case of a tandemly arranged 2lq/2\q translocation that is bisatellited. The varying amounts of the q segments present in the zygosome may account in large measure for the physical and mental deviation of these mongoloid patients from the usual spectrum of characteristics typical of mongoloids bearing three independent chromosomes 21.