Ventral intraparietal area of the macaque: Congruent visual and somatic response properties
Ventral intraparietal area of the macaque: Congruent visual and somatic response properties
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DOI：
10.1152/jn.1998.79.1.126
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发表时间：
1998-01-01
影响因子：
2.5
通讯作者：
Goldberg, ME
中科院分区：
文献类型：
--
作者：
Duhamel, JR;Colby, CL;Goldberg, ME
在之前的一份报告中，我们描述了觉醒猕猴顶叶腹侧区域(VIP区)的视觉反应特性。在这里，我们描述了VIP区的体感反应特性，以及单个神经元对单独给予触觉和视觉刺激的反应之间的对应模式。VIP神经元仅对视觉刺激或视觉和触觉刺激有反应。在测试的218个神经元中，153个(70%)是双峰神经元，因为它们对两种感觉通道中独立施加的刺激有反应。单峰视觉神经元和双峰神经元混合在记录区内，不能仅根据它们的视觉反应特性来区分。大多数具有触觉感受野(RF)的细胞对轻触碰或空气喷雾反应良好。射频位置的分布主要集中在头部(85%)，上面部和下面部区域大致相同。触觉和视觉RFs以一致的方式排列，视觉垂直和水平经络的交点与其触觉对应的鼻子/嘴部区域相对应。小中心凹视觉RFS与口吻上的小触觉RFS配对，而周边视觉RFS与头部或身体一侧的触觉RFS相关。大多数细胞对运动刺激表现出很强的敏感性，85%的双峰细胞的视觉和触觉运动的优先方向一致。在某些情况下，双峰反应模式是互补的：细胞对向猴子的深度运动做出反应的细胞也有反应。而细胞在远离猴子的深处对运动做出反应时，则没有反应。其他形式的双峰反应汇流包括方向选择性，以及开、关和开/关反应类型。VIP区具有一致反应特性的双峰触觉和视觉神经元所占比例较大，这表明VIP区与参与运动分析的其他背流区存在重要的功能差异。我们认为，VIP参与了构建一种多感官的、以头部为中心的近个人外空间的表征。
In a previous report, we described the visual response properties in the ventral intraparietal area (area VIP) of the awake macaque. Here we describe the somatosensory response properties in area VIP and the patterns of correspondence between the responses of single neurons to independently administered tactile and visual stimulation. VIP neurons responded to visual stimulation only or to visual and tactile stimulation. Of 218 neurons tested, 153 (70%) were bimodal in the sense that they responded to stimuli that were independently applied in either sensory modality. Unimodal visual and bimodal neurons were intermingled within the recording area and could not be distinguished on the basis of their visual response properties alone. Most of the cells with a tactile receptive field (RF) responded well to light touch or air puffs. The distribution of RF locations principally emphasized the head (85%), with approximately equivalent representations of the upper and lower face areas. The tactile and visual RFs were aligned in a congruent manner, with the intersection of the visual vertical and horizontal meridian having its tactile counterpart in the nose/mouth area. Small foveal visual RFs were paired with small tactile RFs on the muzzle, and peripheral Visual RFs were associated with tactile RFs on the side of the head or body. Most cells showed a strong sensitivity to moving stimuli, and the preferred directions of visual and tactile motion coincided In 85% of bimodal cells. In some cases, bimodal responses patterns were complementary: cells responding to motion in depth toward the monkey had ON responses. whereas cells responding to motion in depth away form the monkey had OFF responses. Other forms of bimodal response confluence included orientation selectivity, and ON, OFF, and ON/OFF response types. The large proportion of bimodal tactile and visual neurons with congruent response properties in area VIP indicates that there are important functional differences between area VIP and other dorsal stream areas involved in the analysis of motion. We suggest that VIP is involved in the construction of a multisensory, head-centered representation of near extrapersonal space.