Nonsecretory myeloma, immunoglobulin D myeloma, and plasma cell leukemia
Nonsecretory myeloma, immunoglobulin D myeloma, and plasma cell leukemia
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DOI：
10.1016/s0889-8588(05)70125-8
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发表时间：
1999-12-01
影响因子：
2.4
通讯作者：
Kyle, RA
中科院分区：
文献类型：
--
作者：
Bladé, J;Kyle, RA
Nonsecretory myeloma is characterized by the absence of detectable monoclonal protein in serum and urine. It accounts for approximately 2% of all patients with multiple myeloma. Immunoglobulin D myeloma accounts for about 2% of patients with myeloma. Extramedullary plasmacytoma, lambda light chain, and amyloidosis are more common in this disorder. Plasma cell leukemia occurs in about 2% of patients with myeloma. It is primary in 60%, and in the remainder it is secondary as a part of the terminal phase of multiple myeloma. It is more aggressive than multiple myeloma and has a higher frequency of extramedullary involvement, anemia, thrombocytopenia, hypercalcemia, and renal failure.
