Neurodevelopmental Outcomes in Infants Requiring Resuscitation in Developing Countries
Neurodevelopmental Outcomes in Infants Requiring Resuscitation in Developing Countries
复制标题
DOI：
10.1016/j.jpeds.2011.10.007
复制
发表时间：
2012-05-01
影响因子：
5.1
通讯作者：
Wright, Linda L.
中科院分区：
文献类型：
--
作者：
Carlo, Waldemar A.;Goudar, Shivaprasad S.;Wright, Linda L.
目的探讨对出生时不能形成有效呼吸的婴儿进行复苏是否会增加神经发育障碍的幸存者。研究设计在复苏试验中，对刺激无反应的婴儿在出生时接受气囊和面罩通气，以及不需要任何复苏的婴儿随机分为早期神经发育干预组或对照组。婴儿由训练有素的神经发育评估人员进行检查，他们的复苏史和干预组都被掩盖。报告了随机分为对照组的复苏和未复苏婴儿的12个月神经发育结局数据。结果复苏组（86例）和未复苏组（115例）在12个月时智力发育指数的百分比上无明显差异
Objective To determine whether resuscitation of infants who failed to develop effective breathing at birth increases survivors with neurodevelopmental impairment.Study design Infants unresponsive to stimulation who received bag and mask ventilation at birth in a resuscitation trial and infants who did not require any resuscitation were randomized to early neurodevelopmental intervention or control groups. Infants were examined by trained neurodevelopmental evaluators masked to both their resuscitation history and intervention group. The 12-month neurodevelopmental outcome data for both resuscitated and non-resuscitated infants randomized to the control groups are reported.Results The study provided no evidence of a difference between the resuscitated infants (n = 86) and the non-resuscitated infants (n = 115) in the percentage of infants at 12 months with a Mental Developmental Index