Hydrogel Microspheres II. Precipitation Copolymerization of Acrylamide with Comonomers to Prepare Monodisperse Hydrogel Microspheres
Hydrogel Microspheres II. Precipitation Copolymerization of Acrylamide with Comonomers to Prepare Monodisperse Hydrogel Microspheres
复制标题
水凝胶微球 II.
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
Y. Ohtsuka
中科院分区：
文献类型：
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作者：
H. Kawaguchi;Yukino Yamada;S. Kataoka;Y. Morita;Y. Ohtsuka
丙烯酰胺（AAm）和亚甲基双丙烯酰胺（MB）在醇中进行沉淀聚合。通过聚合形成大的、松散的和多孔的颗粒。相反，AAm和MB与一定量的甲基丙烯酸（MAc）共聚导致形成细小的单分散水凝胶微球。这归因于MAc单元对聚合初始阶段形成的颗粒的稳定以及单体和醇对颗粒溶胀的增强的贡献。
Precipitation polymerization of acrylamide (AAm) and methylene-bisacrylamide (MB) was carried out in alcohols. Large, bulky and porous particles were formed by the polymerization. On the contrary, copolymerization of AAm and MB with a certain amount of methacrylic acid (MAc) resulted in the formation of fine monodisperse hydrogel microspheres. This was attributed to the contribution of MAc units to the stabilization of the particles formed at the initial stage of polymerization and the enhancement of swelling of the particles by monomer and alcohol.