Recurrence of mitotically active cellular fibroma of the ovary.
Recurrence of mitotically active cellular fibroma of the ovary.
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DOI：
10.1155/2009/803062
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发表时间：
2009
影响因子：
1.9
通讯作者：
Noël JC
中科院分区：
文献类型：
--
作者：
Bucella D;Limbosch JF;Buxant F;Simon P;Fayt I;Anaf V;Noël JC
背景：10%的卵巢纤维瘤典型表现为细胞增多，有丝分裂活性增强，核异型性少见。因此，在纤维瘤肿瘤组内的分类可能会有一些困难，因此，这些特征中的一个或几个应该出现。的情况。我们介绍了一例复发的有丝分裂活性细胞性卵巢纤维瘤（MACF）在直肠旁窝的临床和病理特点。复发发生在初次手术后6年。宏观上，肿瘤坚固，纤维状，界限分明，黄白色，无明显坏死。显微镜下，它由密集的细胞增生的纤维样细胞组成，细胞核特征温和，呈束状排列。没有明显的异型性或坏死的迹象。结论。最近，该病例是首次报道的MACF复发，在原发性手术后没有肿瘤破裂或手术困难。卵巢细胞纤维瘤（CFs）和MACFs的临床结果通常是平淡无奇的。然而，本病例强烈建议保持长期的临床随访，即使主要肿瘤已手术治疗，肿瘤未破裂或没有依从性或任何手术困难。
Background. 10% of ovarian fibromatous tumours typically exhibit increased cellularity, mitotic activity, and less frequently nuclear atypia. Therefore, the classification within the group of fibromatous tumours may represent some difficulties, thus, one or several of these features should appear. Case. We introduce the clinical and pathologic features based on one case of recurrence of a mitotically active cellular ovarian fibroma (MACF) in the pararectal fossa. This recurrence took place six years after primary surgery. Macroscopically, the tumour was firm, fibrous, well delimited, yellow-white without gross necrosis. On microscopic examination, it was composed of a densely cellular proliferation of fibrolastic-like cells with bland nuclear features and arranged in a fascicular pattern. There was no sign of significant atypia or necrosis. Conclusion. Recently, this case is the first report of a recurrence of MACF, following primary surgery with no tumoral rupture or surgical difficulty. The clinical outcome of ovarian cellular fibromas (CFs) and MACFs is typically uneventful. This case, however, strongly suggests maintaining a long-term clinical follow-up even though the principal tumour was surgically treated without tumour rupture or in the absence of adherence or any surgical difficulty.