TRYPANOSOMA-CRUZI - CORRELATION OF GROWTH-KINETICS TO ZYMODEME TYPE IN CLONES DERIVED FROM VARIOUS SOURCES
TRYPANOSOMA-CRUZI - CORRELATION OF GROWTH-KINETICS TO ZYMODEME TYPE IN CLONES DERIVED FROM VARIOUS SOURCES
复制标题
DOI：
10.1111/j.1550-7408.1980.tb05401.x
复制
发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
MILES, MA
中科院分区：
文献类型：
--
作者：
DVORAK, JA;HARTMAN, DL;MILES, MA
克氏锥虫（裂殖锥虫）克隆来源于急性人类恰加斯病（埃斯梅雷多株）的分离株，人类锥虫病（裂殖锥虫）的分离株。克氏疟原虫感染（菌株CAN-III）和来自自然感染的负鼠（菌株WA-250）。在寄生虫在液体培养基中连续传代的长期培养期间，克隆的同工酶谱和生长速率保持稳定。菌株Esmereldo的两个克隆均为zymode II;菌株CAN-III的2个克隆为zymode III;菌株WA-250的5个克隆为zymode I。在液体培养基中的寄生虫种群的倍增时间的范围是36-49。7 h（菌株WA-250）、117.2-133.7 h（Esmereldo克隆）和169-208 h（CAN-III克隆）。
Trypanosoma(Schizotrypanum)cruziclones were derived from isolates of an acute human case of Chagas' disease (strain Esmereldo), a human case ofT. cruziinfection (strain CAN‐III) and from a naturally infected opossum (strain WA‐250). The isoenzyme patterns and growth rates of the clones were stable during long‐term cultivation, by serial passages, of the parasites in liquid medium. Both clones of strain Esmereldo were zymodeme II; the 2 clones of strain CAN‐III, zymodeme III; and the 5 clones of strain WA‐250, zymodeme I. The range in doubling times of the parasite populations in liquid medium were 36–49. 7 h (strain WA‐250), 117.2–133.7 h (Esmereldo clones) and 169–208 h (CAN‐III clones).