Chemoselective oxidation of alcohols by a H2O2-Pt black system under organic solvent- and halide-free conditions
Chemoselective oxidation of alcohols by a H2O2-Pt black system under organic solvent- and halide-free conditions
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DOI：
10.1002/asia.200800156
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发表时间：
2008-01-01
影响因子：
4.1
通讯作者：
Sato, Kazuhiko
中科院分区：
文献类型：
--
作者：
Kon, Yoshihiro;Yazawa, Hideaki;Sato, Kazuhiko
介绍了用铂黑催化剂在双氧水环境下氧化烯丙醇，得到相应的高收率α、β不饱和羰基化合物。反应在有机溶剂和无卤化物条件下进行。这种铂黑色催化剂是市售的，在催化活性显著丧失之前，至少可以重复使用七次。操作非常简单，即使在百克级的合成中，也能以90%以上的收率得到相应的羰基化合物。还叙述了苯甲醇和仲醇的有效氧化。
Environmentally benign oxidation of allylic alcohols by platinum black catalyst with aqueous hydrogen peroxide to give the corresponding alpha,beta-unsaturated carbonyl compounds in high yield is presented. Reactions are carried out under organic solvent- and halide-free conditions. The platinum black catalyst is commercially available and is found to be reusable at least seven times before significant loss of catalytic activity. The operation is very simple, even in a hectogram-scale synthesis, and gives corresponding carbonyl compounds in over 90% yield. The effective oxidation of benzyl and secondary alcohols are also described.