Interim analysis in clinical trials; the role of the likelihood principle
Interim analysis in clinical trials; the role of the likelihood principle
复制标题
临床试验的中期分析;
DOI:
10.1080/00031305.1987.10475458
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发表时间:
1987
期刊:
影响因子:
--
通讯作者:
D. Berry
中科院分区:
文献类型:
--
作者:
D. Berry
Abstract In the classical statistical approach, whether or not a clinician looks at accumulating data with the possibility of stopping the trial can affect any inferences drawn from the trial. This is in contrast to the Bayesian and likelihood approaches to statistics. I give examples to illustrate the differences in these approaches and discuss designing clinical trials from a Bayesian point of view.