Guidance on Good Cell Culture Practice - A report of the second ECVAM task force on Good Cell Culture Practice
Guidance on Good Cell Culture Practice - A report of the second ECVAM task force on Good Cell Culture Practice
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DOI：
10.1177/026119290503300313
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发表时间：
2005-06-01
影响因子：
2.7
通讯作者：
Stokes, W
中科院分区：
文献类型：
--
作者：
Coecke, S;Balls, M;Stokes, W
保持高标准是所有良好科学实践的基础，对于最大限度地提高所产生的任何结果的可重复性、可靠性、可信度、可接受性和正确应用至关重要。本《细胞培养质量管理规范指南》（GCCP）旨在促进这些标准的维护，并通过鼓励实验室规范、质量控制系统、安全程序、记录和报告以及法律合规性的更大程度的国际协调、合理化和标准化，减少动物和人类细胞及组织培养程序和产品开发和应用中的不确定性。本文件的范围特意作了广泛的界定，以包括基于从人类和动物获得的细胞和组织的系统，以及与基本特征的表征和保持有关的问题，以及质量保证、记录和报告、安全、教育和培训以及伦理。
The maintenance of high standards is fundamental to all good scientific practice, and is essential for maximising the reproducibility, reliability, credibility, acceptance and proper application of any results produced. The aim of this Guidance on Good Cell Culture Practice (GCCP) is to promote the maintenance of these standards and to reduce uncertainty in the development and application of animal and human cell and tissue culture procedures and products, by encouraging greater international harmonisation, rationalisation and standardisation of laboratory practices, quality control systems, safety procedures, recording and reporting, and compliance with laws, regulations and ethical principles.The scope of the document has deliberately been broadly defined, to include systems based on cells and tissues obtained from humans and animals, and issues related to the characterisation and maintenance of essential characteristics, as well as quality assurance, recording and reporting, safety, education and training, and ethics.