Detection of toxigenic Clostridium difficile in diarrheal stools by rapid real-time polymerase chain reaction
Detection of toxigenic Clostridium difficile in diarrheal stools by rapid real-time polymerase chain reaction
复制标题
DOI：
10.1016/j.diagmicrobio.2010.02.019
复制
发表时间：
2010-07-01
影响因子：
2.9
通讯作者：
French, Gary L.
中科院分区：
文献类型：
--
作者：
Goldenberg, Simon D.;Dieringer, Thomas;French, Gary L.
Cepheid Xpert聚合酶链反应检测试剂盒（桑尼维尔，CA）与致突变培养相比，在粪便样本中艰难梭菌的实验室诊断中，灵敏度为100%，特异性为96.7%，阳性和阴性预测值分别为90.5%和100%。该试验似乎是对表现不佳的酶免疫测定的显著改进。(C)2010年爱思唯尔公司All rights reserved.
The Cepheid Xpert polymerase chain reaction assay (Sunnyvale, CA) had a sensitivity of 100%, specificity of 96.7%, and positive and negative predictive values of 90.5% and 100%, respectively, compared with toxigenic culture for the laboratory diagnosis of Clostridium difficile in diarrheal stool samples. This test appears to be a significant improvement to poorly performing enzyme immunoassays. (C) 2010 Elsevier Inc. All rights reserved.