Groove pancreatitis -: An important differential diagnosis to malignant stenosis of the duodenum

Groove pancreatitis -: An important differential diagnosis to malignant stenosis of the duodenum
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DOI:
10.1023/a:1010710011767
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发表时间:
2001-05-01
影响因子:
3.1
通讯作者:
Zeitz, M
Zeitz, M
中科院分区:
医学3区
文献类型:
--
作者:
Mohl, W;Hero-Gross, R;Zeitz, M

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德语术语 Rinnenpankreatitis,后来直译为“凹槽胰腺炎”,Becker 于 1973 年首次使用它来描述一种节段性慢性胰腺炎,涉及胰头、胆总管和十二指肠之间的解剖空间(“凹槽”)(1)。 1982年,Becker小组的成员报道了慢性胰腺炎十二指肠胰腺切除术后的123例切除者中有30例出现沟型胰腺炎(2)。他们区分了真正的胰腺炎和节段性胰腺炎,如果仅在沟内发现疤痕,则使用术语“纯沟型胰腺炎”,如果胰头的背颅部分也受累,则使用“节段性沟型胰腺炎”。主要形态学特征包括节段性疤痕组织取代胰腺实质以及胆管至多最小扩张。经常发现十二指肠壁的疤痕和狭窄,并伴有布伦纳腺增生。 “几乎所有”标本中都存在胆总管的套箍或包裹,而纯胆管和节段性胆管狭窄分别占 67% 和 27%。作者得出的结论是,这些特征可能有助于将该疾病与胰腺癌区分开来,后者通常不存在布伦纳腺增生,十二指肠狭窄较少见,管状胆管狭窄罕见。相反,胰腺癌通常表现为胆管和胰管不规则狭窄。无显着性
The German term Rinnenpankreatitis, later literally translated to “groove pancreatitis,” was first used in 1973 by Becker to describe a segmental type of chronic pancreatitis, which involves the anatomic space (“groove”) between pancreatic head, common bile duct, and duodenum (1). In 1982, members of Becker's group reported 30 cases of groove pancreatitis among 123 resectates after duodenopancreatectomy for chronic pancreatitis (2). They distinguished between a genuine and a segmental form, using the term “pure groove pancreatitis” in cases where scarring was only found in the groove,“segmental groove pancreatitis” if dorsocranial parts of the pancreatic head were also involved. The main morphologic features included replacement of pancreatic parenchyma by scar tissue in the segmental form and at most minimal dilatation of the biliary duct. Cicatrization and stenosis of the duodenal wall, accompanied by hyperplasia of Brunner's glands has often been identified. Cuffing or encasement of the common bile duct was present in “almost all'" specimens, while duct stenosis was seen in 67% and 27% of pure and segmental forms, respectively. The authors concluded that these features might help to distinguish the disease from pancreatic carcinoma, where hyperplasia of Brunner's glands is usually absent, duodenal stenosis less frequent, and tubular bile duct stenosis rare. Pancreatic carcinoma instead usually shows irregular stenosis of biliar and pancreatic duct. No significant