Lifestyle modifications in the management of type 1 diabetes: still relevant after all these years?
Lifestyle modifications in the management of type 1 diabetes: still relevant after all these years?
复制标题
生活方式改变在 1 型糖尿病治疗中的作用：这么多年过去了，仍然有意义吗？
DOI：
10.1089/dia.2014.0175
复制
发表时间：
2014
影响因子：
5.4
通讯作者：
Gonder-Frederick,Linda
中科院分区：
文献类型：
--
作者：
Gonder-Frederick,Linda
随着我们进入21世纪，1型糖尿病（T1D）的研究和治疗的前景正在经历巨大的转变，其特征在于许多科学前沿的快速进步，包括胰岛素和其他激素疗法、血糖（BG）监测和胰岛素递送技术、干细胞疗法、基因工程、b细胞移植、甚至异种移植。显然，这些科学进步对未来的糖尿病管理具有巨大的影响。这些快速发展和前沿发现也可能对我们关于糖尿病管理的不同方面如何在研究和患者护理中优先考虑的观点产生重要但并不总是明显的影响。例如，随着最近的技术突破，特别是与闭环控制（CLC）或人工胰腺（AP）相关的技术突破所产生的热情，是否有理由担心T1D管理的更传统（可能不那么“令人兴奋”）的方面，如生活方式的改变，在研究和糖尿病护理中会受到较少的关注？生活方式因素（包括饮食和运动）与T1D治疗的当代观点和实践有多大关系？他们在未来的糖尿病管理中将发挥什么作用？本专栏探讨了最近的科学进步对T1D治疗中生活方式改变的重要性的态度的潜在影响，以及越来越倾向于低估其作为临床结果的基本决定因素的作用的可能性。对于T1D和2型糖尿病（T2D），生活方式改变一直是，并且仍然是糖尿病管理中最艰巨的任务之一。令人惊讶的是，有证据表明，与没有糖尿病的同龄人相比，患有T1D的青年和成年人的饮食和体育活动习惯实际上更差。1-5出于这个原因，它是有吸引力的设想未来的技术，如CLC系统，将提供一个解决方案的问题，生活方式的改变。当然，自动血糖控制的主要目标是通过改善血糖状态和医疗结果来使T1D患者（以及有一天患有T2D的患者）受益。6同样重要的是，
As we progress into the 21 st century, the landscape of research and treatment in type 1 diabetes (T1D) is undergoing a massive transformation, characterized by rapid advances on numerous scientific fronts, including insulin and other hormonal therapies, technologies for blood glucose (BG) monitoring and insulin delivery, stem cell therapies, genetic engineering, b-cell transplantation, and even xenotransplantation. Clearly, these scientific advances have enormous implications for future diabetes management. These rapid developments and cutting-edge discoveries may also have important, but not always obvious, implications for our perspectives on how different aspects of diabetes management should be prioritized in research and patient care. For example, with the enthusiasm generated by recent technological breakthroughs, especially those associated with closed-loop control (CLC) or the artificial pancreas (AP), is there a reason to be concerned that more traditional (and perhaps less ‘‘exciting’’) aspects of T1D management, such as lifestyle modifications, will receive less attention in research and diabetes care? How relevant are lifestyle factors, including diet and exercise, to contemporary views and practice of T1D treatment? What role will they play in future diabetes management? This column explores the potential impact of recent scientific advances on attitudes regarding the importance of lifestyle modification in T1D treatment, as well as the possibility that there is a growing tendency to undervalue their role as essential determinants of clinical outcome.For both T1D and type 2 diabetes (T2D), lifestyle modification has always been, and remains, one of the most formidable tasks in diabetes management. It is somewhat surprising that there is evidence that dietary as well as physical activity habits are actually poorer in both youth and adults with T1D than their peers without diabetes. 1–5 For this reason, it is appealing to envision a future in which technology, such as CLC systems, would offer a solution to the problem of lifestyle modification. The primary goal of automated glucose control is, of course, to benefit T1D individuals (and someday those with T2D) by improving glycemic status and medical outcome. 6 Just as important,
登录
查看更多内容
影响因子：
158.5
作者：
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者：
Nathan, DM
营养师就诊、糖尿病课程以及住院费用和费用
影响因子：
16.2
作者：
J. Robbins;G. Thatcher;D. Webb;V. Valdmanis
通讯作者：
V. Valdmanis
影响因子：
5.1
作者：
Speight, J.;Amiel, S. A.;Thompson, G.
通讯作者：
Thompson, G.
影响因子：
3.4
作者：
Lukacs, Andrea;Mayer, Krisztina;Barkai, Laszlo
通讯作者：
Barkai, Laszlo
影响因子：
16.2
作者：
Evert AB;Boucher JL;Cypress M;Dunbar SA;Franz MJ;Mayer-Davis EJ;Neumiller JJ;Nwankwo R;Verdi CL;Urbanski P;Yancy WS Jr;American Diabetes Association
通讯作者：
American Diabetes Association