BiNoM: a Cytoscape plugin for manipulating and analyzing biological networks

BiNoM: a Cytoscape plugin for manipulating and analyzing biological networks
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DOI:
10.1093/bioinformatics/btm553
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发表时间:
2008-03-01
期刊:
影响因子:
5.8
通讯作者:
Barillot, Emmanuel
Barillot, Emmanuel
中科院分区:
生物学3区
文献类型:
--
作者:
Zinovyev, Andrei;Viara, Eric;Barillot, Emmanuel

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BiNoM(Biological Network Manager)是一个新的生物信息学软件,它极大地促进了标准系统生物学格式(SBML,SBGN,BioPAX)中生物网络的使用和分析。BiNoM实现了一个全功能的BioPAX编辑器和一个访问BioPAX内容的“接口”方法。BiNoM能够处理庞大的BioPAX文件,如整个途径数据库。此外,BiNoM允许分析使用CellDesigner软件创建的网络并将其转换为BioPAX格式。BiNoM是一个库和Cytoscape插件,它为Cytoscape添加了一组丰富的操作,如路径和循环分析,子网络聚类,网络分解为模块,剪贴板操作等。
BiNoM (Biological Network Manager) is a new bioinformatics software that significantly facilitates the usage and the analysis of biological networks in standard systems biology formats (SBML, SBGN, BioPAX). BiNoM implements a full-featured BioPAX editor and a method of 'interfaces' for accessing BioPAX content. BiNoM is able to work with huge BioPAX files such as whole pathway databases. In addition, BiNoM allows the analysis of networks created with CellDesigner software and their conversion into BioPAX format. BiNoM comes as a library and as a Cytoscape plugin which adds a rich set of operations to Cytoscape such as path and cycle analysis, clustering sub-networks, decomposition of network into modules, clipboard operations and others.