Distance between intramuscular nerve and artery in the extraocular muscles: a preliminary immunohistochemical study using elderly human cadavers
Distance between intramuscular nerve and artery in the extraocular muscles: a preliminary immunohistochemical study using elderly human cadavers
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DOI：
10.1007/s00276-016-1642-9
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发表时间：
2017-01-01
影响因子：
1.4
通讯作者：
Abe, Shin-ichi
中科院分区：
文献类型：
--
作者：
Kitamura, Kei;Cho, Kwang Ho;Abe, Shin-ichi
眼外肌在肌纤维类型和神经供应方面与骨骼肌有很大不同;小运动单位可能是最知名的。为了解眼外肌的神经-动脉关系，我们测量了眼外肌内微动脉（25-50 μ m厚）至神经末梢的距离，并对10具老年人尸体的68块眼外肌，用免疫组织化学方法，对各10-15个部位的微动脉-神经距离进行了观察。斜切面几乎与肌板相切，包括肌肉的整体和眶部，在所有肌肉中，神经分支通常平行于肌纤维走行，而大多数小动脉穿过肌肉。可能是由于多神经支配，肌内神经丛是明显的四直肌和两个斜肌。小动脉-神经的距离一般在300 ~ 400 μ m之间。然而，在七块肌肉中，每一块肌肉的个体差异都要大两倍以上。此外，在每块肌肉中，部位之间的差异有时达到1 mm或更多。直肌和斜肌的微动脉-神经距离普遍短于提睑肌，差异有统计学意义（p <0. 05）。
Extraocular muscles are quite different from skeletal muscles in muscle fiber type and nerve supply; the small motor unit may be the most well known. As the first step to understanding the nerve-artery relationship, in this study we measured the distance from the arteriole (25-50 mu m in thickness) to the nerve terminal twigs in extraocular muscles.With the aid of immunohistochemistry for nerves and arteries, we examined the arteriole-nerve distance at 10-15 sites in each of 68 extraocular muscles obtained from ten elderly cadavers. The oblique sections were nearly tangential to the muscle plate and included both global and orbital aspects of the muscle.In all muscles, the nerve twigs usually took a course parallel to muscle fibers, in contrast to most arterioles that crossed muscles. Possibly due to polyinnervation, an intramuscular nerve plexus was evident in four rectus and two oblique muscles. The arteriole-nerve distance usually ranged from 300 to 400 mu m. However, individual differences were more than two times greater in each of seven muscles. Moreover, in each muscle the difference between sites sometimes reached 1 mm or more. The distance was generally shorter in the rectus and oblique muscles than in the levator palpebrae muscle, which reached statistical significance (p < 0.05).The differences in arteriole-nerve distances between sites within each muscle, between muscles, and between individuals might lead to an individual biological rhythm of fatigue in oculomotor performance.