Family size and perinatal circumstances, as mental health risk factors in a Scottish birth cohort
Family size and perinatal circumstances, as mental health risk factors in a Scottish birth cohort
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DOI：
10.1007/s00127-011-0405-5
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发表时间：
2012-06-01
影响因子：
4.4
通讯作者：
Stark, Cameron
中科院分区：
文献类型：
--
作者：
Riordan, Daniel Vincent;Morris, Carole;Stark, Cameron
较高的产妇产次和较年轻的产妇年龄已被观察到与随后的后代自杀行为。本研究旨在确定这些因素以及围产期的其他变量，以及家庭规模，是否也与其他精神病发病率相关，并使用苏格兰发病率记录和苏格兰死亡记录的关联数据集对897，685名出生队列进行随访，直至成年。除了索引生育记录外，还查明了母亲随后的怀孕记录，从而可以估计家庭规模。三个独立的结果进行了研究：自杀，自我伤害，精神病院入院。数据分析采用考克斯回归。年轻的母亲年龄和较高的产妇产次独立地与后代的自杀，自残和精神病入院的风险增加。来自三口或三口以上家庭的儿童精神病入院风险较高，但与独生子女相比，有两个或三个兄弟姐妹的儿童自我伤害风险较低。围产期和家庭组成因素对心理健康结果有广泛的影响。这些数据表明，弟弟妹妹和哥哥姐姐的存在可能很重要。
Higher maternal parity and younger maternal age have each been observed to be associated with subsequent offspring suicidal behaviour. This study aimed to establish if these, and other variables from the perinatal period, together with family size, are also associated with other psychiatric morbidity.Linked datasets of the Scottish Morbidity Record and Scottish death records were used to follow up, into young adulthood, a birth cohort of 897,685. In addition to the index maternity records, mothers' subsequent pregnancy records were identified, allowing family size to be estimated. Three independent outcomes were studied: suicide, self-harm, and psychiatric hospital admission. Data were analysed using Cox regression.Younger maternal age and higher maternal parity were independently associated with increased risk in offspring of suicide, of self-harm and of psychiatric admission. Risk of psychiatric admission was higher amongst those from families of three or more, but, compared with only children, those with two or three siblings had a lower risk of self harm.Perinatal and family composition factors have a broad influence on mental health outcomes. These data suggest that the existence of younger, as well as elder siblings may be important.