Surgery in sickle cell disease
Surgery in sickle cell disease
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DOI：
10.1016/j.hoc.2005.07.004
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发表时间：
2005-10-01
影响因子：
2.4
通讯作者：
Davies, SC
中科院分区：
文献类型：
--
作者：
Buck, J;Davies, SC
由于镰状细胞病（SCD）并发症的性质，患有这种疾病的人在其一生中比一般人群更有可能接受手术。例如，胆囊切除术作为胆囊结石的结果在SCD患者中更常见，髋关节成形术在年轻人中由于股骨头缺血性坏死而更常见。由于手术使患者暴露于许多已知会促使红细胞镰状化的因素，因此接受手术的SCD患者需要细致的临床护理，以预防围手术期镰状细胞相关并发症。即使经过精心护理，约25%至30%的患者仍会发生术后并发症[1，2]。本文为读者提供了有关外科手术在SCD中的作用的信息，以及为确保患者在围手术期得到良好护理而应采取的措施。
Because of the nature of the complications of sickle cell disease (SCD), persons with this illness are more likely to undergo surgery than are the general population during their lifetime. For example, cholecystectomy as a consequence of gallstones is more frequent in persons with SCD, as is hip arthroplasty in younger people as a result of avascular necrosis of the femoral head. Because surgery exposes patients to many of the factors that are known to precipitate red blood cell sickling, persons With SCD undergoing surgery require meticulous clinical care to prevent perioperative sickle cell-related complications. Even with meticulous care, approximately 25% to 30% of patients will have a postoperative complication [1,2]. This article provides readers with information about the role of surgery in SCD and the measures that should be taken to ensure patients are well cared for in the perioperative period.