Antiplatelet drug non responsiveness
Antiplatelet drug non responsiveness
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DOI：
10.1016/j.ahj.2007.12.034
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发表时间：
2008-04-01
影响因子：
4.8
通讯作者：
White, Harvey
中科院分区：
文献类型：
--
作者：
Gladding, Patrick;Webster, Mark;White, Harvey
对大多数药物的反应，包括抗血小板药物，因人而异。观察性研究表明，对抗血小板药物无效的患者血管事件的发生率似乎增加。这篇综述文章回顾了这一现象的背景、机制和支持其临床意义的证据。
The response to most medication, including antiplatelet drugs, is highly variable between individuals. Observational studies have shown that nonresponders to antiplatelet agents appear to have an increased incidence of vascular events. This review article reviews the background, mechanisms, and evidence in support of the clinial significance of this phenomenon.