Alcohol Consumption, Weight Gain, and Risk of Becoming Overweight in Middle-aged and Older Women
Alcohol Consumption, Weight Gain, and Risk of Becoming Overweight in Middle-aged and Older Women
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DOI：
10.1001/archinternmed.2009.527
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发表时间：
2010-03-08
影响因子：
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通讯作者：
Sesso, Howard D.
中科院分区：
文献类型：
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作者：
Wang, Lu;Lee, I-Min;Sesso, Howard D.
背景：肥胖流行是美国的一个主要健康问题。酒精消费是一种能量摄入来源，可能导致体重增加和肥胖症的发展。然而，以前对这种关系的研究有限，结果不一致。方法：我们在19220名年龄在38.9岁或以上的美国女性中进行了一项前瞻性队列研究，这些女性没有心血管疾病，癌症和糖尿病，基线体重指数（BMI;计算为体重（千克）除以身高（米）的平方）在18.5至小于25的正常范围内。在基线问卷中报告了酒精饮料消费量。体重是自我报告的基线和8个年度随访questionnaire.Results：有一个负相关的基线和体重增加在12.9年的随访期间的酒精消耗量之间。共有7942名（41.3%）最初体重正常的妇女变得超重或肥胖（BMI >= 25），732名（3.8%）变得肥胖（BMI >= 30）。在调整了年龄、基线BMI、吸烟状况、非酒精能量摄入、身体活动水平和其他生活方式和饮食因素后，总酒精摄入量为0、大于0至小于5、5至小于15、15至小于30和30 g/d或以上的超重或肥胖的相对风险分别为1.00、0.96、0.86、0.70、0.96、0.86、0.70、0.97、0.98、0.99和0.99。和0.73（P趋势
Background: The obesity epidemic is a major health problem in the United States. Alcohol consumption is a source of energy intake that may contribute to body weight gain and development of obesity. However, previous studies of this relationship have been limited, with inconsistent results.Methods: We conducted a prospective cohort study among 19 220 US women aged 38.9 years or older who were free of cardiovascular disease, cancer, and diabetes mellitus and had a baseline body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) within the normal range of 18.5 to less than 25. Alcoholic beverage consumption was reported on a baseline questionnaire. Body weight was self-reported on baseline and 8 annual follow-up questionnaires.Results: There was an inverse association between amount of alcohol consumed at baseline and weight gained during 12.9 years of follow-up. A total of 7942 (41.3%) initially normal-weight women became over-weight or obese (BMI >= 25) and 732 (3.8%) became obese (BMI >= 30). After adjusting for age, baseline BMI, smoking status, nonalcohol energy intake, physical activity level, and other lifestyle and dietary factors, the relative risks of becoming overweight or obese across total alcohol intake of 0, more than 0 to less than 5, 5 to less than 15, 15 to less than 30, and 30 g/d or morewere 1.00, 0.96, 0.86, 0.70, and 0.73, respectively (P for trend