Statistical properties of phase-decorrelation in phase-resolved Doppler optical coherence tomography.
Statistical properties of phase-decorrelation in phase-resolved Doppler optical coherence tomography.
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DOI：
10.1109/tmi.2009.2012891
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发表时间：
2009-06
影响因子：
10.6
通讯作者：
Bouma BE
中科院分区：
文献类型：
--
作者：
Vakoc BJ;Tearney GJ;Bouma BE
去相关噪声限制了相位分辨多普勒光学相干断层扫描系统检测流速较慢的较小血管的能力，这限制了该技术在许多临床和生物环境中的实用性。了解去相关噪声的统计特性有助于这些系统的优化设计并指导噪声缓解策略的开发。在这项工作中，去相关噪声的统计特性是从相干成像系统的基础统计数据中得出的，并通过与经验结果和蒙特卡罗建模的比较进行验证。给出了噪声分布和噪声方差作为相关成像系统参数的函数的表达式，并讨论了这些结果对系统和算法设计的影响。
Decorrelation noise limits the ability of phase-resolved Doppler optical coherence tomography systems to detect smaller vessels exhibiting slower flow velocities, which limits the utility of the technique in many clinical and biological settings. An understanding of the statistical properties of decorrelation noise can aid in the optimal design of these systems and guide the development of noise mitigating strategies. In this work, the statistical properties of decorrelation noise are derived from the underlying statistics of the coherent imaging system and validated through comparison with empirical results and Monte Carlo modeling. Expressions for the noise distribution and the noise variance as a function of relevant imaging system parameters are given, and the implications of these results on both system and algorithm design are discussed.