Multiple-pyrene residues arrayed along DNA backbone exhibit significant excimer fluorescence
Multiple-pyrene residues arrayed along DNA backbone exhibit significant excimer fluorescence
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DOI：
10.1016/j.tetlet.2004.03.074
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发表时间：
2004-05-10
影响因子：
1.8
通讯作者：
Ono, A
中科院分区：
文献类型：
--
作者：
Kosuge, M;Kubota, M;Ono, A
通过在寡脱氧核糖核苷酸（ODNs）中引入一种新的核苷-芘结合物，制备了多芘簇的ODNs。多个芘残基在DNA链上的排列诱导了明显的准分子荧光，其强度随芘残基数目的增加呈指数增加。该阵列的受激准分子荧光稳定，不会被双链体形成所猝灭。(C)2004爱思唯尔有限公司保留所有权利。
Oligodeoxyribonuelcotides (ODNs) carrying multi-pyrene clusters were chemically prepared by introducing a novel nucleoside-pyrene conjugate into ODNs. The multi-pyrene residues arrayed on DNA strands induced significant excimer fluorescence and the intensity was exponentially increased as the number of pyrene residues in clusters increased. The excimer fluorescence of the arrays was stable and was not quenched by duplex formation. (C) 2004 Elsevier Ltd. All rights reserved.