Ex vivo and in vivo OCT image contrast
Ex vivo and in vivo OCT image contrast
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离体和体内 OCT 图像对比
DOI：
10.1117/12.819495
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发表时间：
2008
影响因子：
3.1
通讯作者：
S. Matcher
中科院分区：
文献类型：
--
作者：
N. Krstajić;J. Jacobs;M. Bonesi;L. Smith;P. Deshpande;S. Macneil;R. Smallwood;S. Matcher
We present results of OCT and polarization-OCT applied to various ex vivo tissue samples and discuss related issues of image contrast, comparing in vivo and ex vivo preparations. Time-domain and frequency-domain OCT at 835nm and 1300nm have been applied to ex vivo skin and rabbit cornea. We can distinguish rabbit cornea epithelium for up to a month after excision. However, the skin loses all contrast upon excision and despite numerous experiments we cannot distinguish epidermis, which is clearly visible in vivo. Using a time-domain system, birefringence is clearly visible for decalcified tissue but can also be detected more weakly on fully mineralised tissue. Analysis suggests that demineralization increases the birefringence value.
影响因子：
1.7
作者：
Ripandelli, G;Coppe, A M;Stirpe, M
通讯作者：
Stirpe, M