Selectivity properties of pores induced in host erythrocyte membrane by Plasmodium falciparum. Effect of parasite maturation.

Selectivity properties of pores induced in host erythrocyte membrane by Plasmodium falciparum. Effect of parasite maturation.
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恶性疟原虫在宿主红细胞膜上诱导的孔的选择性特性。

DOI:
10.1016/0005-2736(86)90579-1
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发表时间:
1986
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
Cabantchik,ZI
Cabantchik,ZI
中科院分区:
--
文献类型:
--
作者:
Ginsburg,H;Kutner,S;Zangwil,M;Cabantchik,ZI

文献摘要

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The intraerythrocytic malarial parasite permeabilizes its host cell membrane by inducing pore-like pathways which mediate the passage of nonelectrolytes and anions. In the present work we show that, although the permeability increases with parasite maturation, the selectivity of the pores to various solutes is essentially preserved, suggesting that the number of pores increases without any alteration in their intrinsic solute conductance.