Prevalence and Pattern of Chronic Kidney Disease in Antiretroviral-Naive Patients with HIV/AIDS.
Prevalence and Pattern of Chronic Kidney Disease in Antiretroviral-Naive Patients with HIV/AIDS.
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DOI：
10.1177/2325957415587570
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发表时间：
2015-09-01
影响因子：
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通讯作者：
Jimoh, Kayode A
中科院分区：
文献类型：
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作者：
Adedeji, Tewogbade Adeoye;Adedeji, Nife O;Jimoh, Kayode A
背景：慢性肾衰竭和艾滋病毒/艾滋病在尼日利亚都很流行。在开始高效抗逆转录病毒治疗之前，我们对新诊断、未接受过治疗的 HIV 感染患者的肾功能进行了横断面分析。方法：招募了没有治疗经验的个体。患有糖尿病和高血压的患者被排除在外。血浆肌酐水平用于测量估计的肾小球滤过率（[eGFR]，通过修改肾脏疾病方程中的饮食）。通过单变量和多变量分析确定肌酐和 eGFR 的预测因子。 结果：我们评估了 183 名患者。总共 44 名 (24%) 患者有 GFR
BACKGROUND: Chronic renal failure and HIV/AIDS are both prevalent in Nigeria. We performed a cross-sectional analysis of renal function in newly diagnosed, treatment-naive HIV-infected patients before initiating highly active antiretroviral therapy.METHODS: Treatment-inexperienced individuals were recruited. Patients with diabetes mellitus and hypertension were excluded. Plasma creatinine level was used to measure the estimated glomerular filtration rate ([eGFR] by Modification of Diet in Renal Disease equation). Predictors of creatinine and eGFR were determined by univariate and multivariate analyses.RESULTS: We evaluated 183 patients. In all, 44 (24%) patients had a GFR