Nanotechnology-based drug delivery for cancer
Nanotechnology-based drug delivery for cancer
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DOI：
10.1177/153303460500400408
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发表时间：
2005-08-01
影响因子：
2.8
通讯作者：
Jain, KK
中科院分区：
文献类型：
--
作者：
Jain, KK
纳米生物技术已被应用于改善药物递送和克服癌症中药物递送的一些问题。这些可以分为许多类别，包括使用各种纳米颗粒，纳米封装，靶向递送到各种器官的肿瘤，以及与其他治疗癌症的方法如放射疗法相结合。纳米颗粒也用于癌症的基因治疗。其中一些技术能够将诊断与治疗相结合，这对于癌症的个性化管理至关重要。这些技术的局限性和未来的发展前景进行了讨论。
Nanobiotechnologies have been applied to improve drug delivery and to overcome some of the problems of drug delivery in cancer. These can be classified into many categories that include use of various nanoparticles, nanoencapsulation, targeted delivery to tumors of various organs, and combination with other methods of treatment of cancer such as radiotherapy. Nanoparticles are also used for gene therapy for cancer. Some of the technologies enable combination of diagnostics with therapeutics which will be important for the personalized management of cancer. Some of the limitations of these technologies and prospects for future development are discussed.