Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies
复制标题
急性肺损伤/急性呼吸窘迫综合征（ALI/ARDS）：治疗的机制、现有策略及未来展望
DOI：
10.1631/jzus.2007.b0060
复制
发表时间：
2007-01-01
影响因子：
5.1
通讯作者：
Chiang Chi-Huei
中科院分区：
文献类型：
--
作者：
Luh Shi-Ping;Chiang Chi-Huei
急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)表现为非心源性肺水肿、呼吸窘迫和低氧血症，可由多种直接或间接损伤肺的过程引起。在实验模型和人类ALI/ARDS中的广泛研究揭示了许多分子机制，为细胞或基因治疗提供了治疗机会。目前治疗ALI/ARDS的策略和前景包括呼吸机疗法、药物疗法和细胞疗法。
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), which manifests as non-cardiogenic pulmonary edema, respiratory distress and hypoxemia, could be resulted from various processes that directly or indirectly injure the lung. Extensive investigations in experimental models and humans with ALI/ARDS have revealed many molecular mechanisms that offer therapeutic opportunities for cell or gene therapy. Herein the present strategies and future perspectives of the treatment for ALI/ARDS, include the ventilatory, pharmacological, as well as cell therapies.