Anterior Cingulate Activation Is Related to a Positivity Bias and Emotional Stability in Successful Aging
Anterior Cingulate Activation Is Related to a Positivity Bias and Emotional Stability in Successful Aging
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DOI：
10.1016/j.biopsych.2010.10.013
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发表时间：
2011-07-15
影响因子：
10.6
通讯作者：
Buechel, Christian
中科院分区：
文献类型：
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作者：
Brassen, Stefanie;Gamer, Matthias;Buechel, Christian
背景：行为研究一致报道老年人对积极体验的偏好增加。社会情绪选择性理论解释了这种积极性效应与情绪调节的动机性目标转移，这可能取决于可用的认知资源。本研究探讨的神经生物学机制，这一hypothes.Methods：功能磁共振成像数据采集在21个老年人和22个年轻的科目，同时执行一个空间线索范式，操纵注意力负荷的情绪面孔分心。我们把我们的分析集中在前扣带皮层作为一个关键结构的认知控制emotions.Results：老年受试者表现出一个特别增加分心快乐的面孔时，更多的注意力资源可用于面部处理。这种效果是由增加参与喙前扣带皮层，这种额叶的参与显着相关的情绪stability.Conclusions：目前的研究强调了大脑如何可能介导的倾向，优先从事积极的信息处理在健康老龄化。这种积极性效应的资源依赖性的发现表明，要求自我调节过程与情绪健康有关。这些发现对于理解、治疗和预防不成功的衰老（如高度流行的晚年抑郁症）具有特别重要的意义。
Background: Behavioral studies consistently reported an increased preference for positive experiences in older adults. The socio-emotional selectivity theory explains this positivity effect with a motivated goal shift in emotion regulation, which probably depends on available cognitive resources. The present study investigates the neurobiological mechanism underlying this hypothesis.Methods: Functional magnetic resonance imaging data were acquired in 21 older and 22 young subjects while performing a spatial-cueing paradigm that manipulates attentional load on emotional face distracters. We focused our analyses on the anterior cingulate cortex as a key structure of cognitive control of emotion.Results: Elderly subjects showed a specifically increased distractibility by happy faces when more attentional resources were available for face processing. This effect was paralleled by an increased engagement of the rostral anterior cingulate cortex, and this frontal engagement was significantly correlated with emotional stability.Conclusions: The current study highlights how the brain might mediate the tendency to preferentially engage in positive information processing in healthy aging. The finding of a resource-dependency of this positivity effect suggests demanding self-regulating processes that are related to emotional well-being. These findings are of particular relevance regarding implications for the understanding, treatment, and prevention of nonsuccessful aging like highly prevalent late-life depression.