Neonatal Abstinence Syndrome and Associated Health Care Expenditures United States, 2000-2009
Neonatal Abstinence Syndrome and Associated Health Care Expenditures United States, 2000-2009
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DOI：
10.1001/jama.2012.3951
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发表时间：
2012-05-09
影响因子：
120.7
通讯作者：
Davis, Matthew M.
中科院分区：
文献类型：
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作者：
Patrick, Stephen W.;Schumacher, Robert E.;Davis, Matthew M.
背景 新生儿戒断综合征 (NAS) 是一种主要由母亲使用阿片类药物引起的产后戒毒综合征。没有关于产妇在分娩时使用阿片类药物或 NAS 的发生率的全国估计。 目的 确定全国 NAS 和产前产妇阿片类药物使用的发生率，并描述 2000 年至 2009 年间与 NAS 相关的国家医疗保健支出趋势。 设计、环境和患者 对具有全国代表性的 NAS 新生儿样本进行回顾性、系列、横断面分析。儿童住院数据库 (KID) 用于根据国际疾病分类第九版临床修改 (ICD-9-CM) 代码识别患有 NAS 的新生儿。全国住院患者样本 (NIS) 用于通过阴道分娩和剖腹产诊断相关组来识别母亲。使用 ICD-9-CM 诊断代码来识别临床状况。 NAS 和孕产妇阿片类药物使用率被描述为每年每 1000 名医院分娩的频率。缺少医院费用（
Context Neonatal abstinence syndrome (NAS) is a postnatal drug withdrawal syndrome primarily caused by maternal opiate use. No national estimates are available for the incidence of maternal opiate use at the time of delivery or NAS.Objectives To determine the national incidence of NAS and antepartum maternal opiate use and to characterize trends in national health care expenditures associated with NAS between 2000 and 2009.Design, Setting, and Patients Aretrospective, serial, cross-sectional analysis of a nationally representative sample of newborns with NAS. The Kids' Inpatient Database (KID) was used to identify newborns with NAS by International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) code. The Nationwide Inpatient Sample (NIS) was used to identify mothers using diagnosis related groups for vaginal and cesarean deliveries. Clinical conditions were identified using ICD-9-CM diagnosis codes. NAS and maternal opiate use were described as an annual frequency per 1000 hospital births. Missing hospital charges (