Estimation of magnetic moment and anisotropy energy of magnetic markers for biosensing application
Estimation of magnetic moment and anisotropy energy of magnetic markers for biosensing application
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DOI：
10.1063/1.4948951
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发表时间：
2016-05-14
影响因子：
3.2
通讯作者：
Yoshida, T.
中科院分区：
文献类型：
--
作者：
Enpuku, K.;Sasayama, T.;Yoshida, T.
我们提出了一种方法来评估磁矩（m）和各向异性能量（E）的磁性标记，这是在生物传感应用中使用的关键参数。通过分析悬浮标记的静态磁化（M-H）曲线和固定标记的交流磁化率的频率依赖性，分别评估标记中的m和E值的分布。然后，我们得到m和E之间的关系。在实验中，检查了由多核和单核纳米颗粒制成的四种标记物。我们得到的m和E值的分布，这表明每个标记的特定特征。虽然m和E值在标记中广泛分布，但在这些值之间获得了明确的关系。因此，所获得的m-E曲线，以及m和E值的分布，提供了一个框架来讨论固定化标记物的动态行为。还讨论了标记物之间的估计的m-E曲线的差异。由AIP出版社出版。
We present a method to evaluate the magnetic moment (m) and the anisotropy energy (E) of magnetic markers, which are the key parameters employed in biosensing applications. The distributions of the m and E values in the marker are evaluated by analyzing the static magnetization (M-H) curve of the suspended markers and the frequency dependence of the AC susceptibility of the immobilized markers, respectively. Then, we obtain the relationship between m and E. In the experiment, four markers made of multicore and single core nanoparticles are examined. We obtain distributions of the m and E values, which show the particular characteristics of each marker. Although the m and E values are widely distributed in the marker, a clear relationship is obtained between the values. Therefore, the obtained m-E curve, as well as the distribution of the m and E values, provides a framework to discuss the dynamic behavior of the immobilized markers. The difference in the estimated m-E curves between the markers is also discussed. Published by AIP Publishing.