Eradication of a Multidrug-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Isolate Following Oral and Intra-rectal Therapy With a Custom Made, Lytic Bacteriophage Preparation
Eradication of a Multidrug-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Isolate Following Oral and Intra-rectal Therapy With a Custom Made, Lytic Bacteriophage Preparation
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DOI：
10.1093/cid/ciz782
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发表时间：
2020-05-01
影响因子：
11.8
通讯作者：
Poirel, Laurent
中科院分区：
文献类型：
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作者：
Corbellino, Mario;Kieffer, Nicolas;Poirel, Laurent
2017年7月，1例患者出现多重耐药、产碳青霉烯酶（KPC-3）的肺炎克雷伯菌分离株定植。2017年12月，患者接受了定制的裂解性噬菌体制剂，随后根除了微生物，没有不良反应。
In July 2017, a patient presented colonization with a multidrug-resistant, carbapenemase (KPC-3)-producing Klebsiella pneumoniae isolate. A custom-made, lytic bacteriophage preparation was administered to the patient in December 2017, with subsequent eradication of the microorganism and without adverse effects.