Influence of panic-agoraphobic spectrum symptoms on treatment response in patients with recurrent major depression
Influence of panic-agoraphobic spectrum symptoms on treatment response in patients with recurrent major depression
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DOI：
10.1176/appi.ajp.157.7.1101
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发表时间：
2000-07-01
影响因子：
17.7
通讯作者：
Cassano, GB
中科院分区：
文献类型：
--
作者：
Frank, E;Shear, MK;Cassano, GB
Objective: The authors tested the hypothesis that a lifetime history of panicagoraphobic spectrum symptoms predicts a poorer response to depression treatment.Method: A threshold for clinically meaningful panic-agoraphobic spectrum symptoms was defined by means of receiver operating characteristic curve analysis of total scores on the Structured Clinical Interview for Panic-Agoraphobic Spectrum in a group of 88 outpatients with and without panic disorder. This threshold was then applied to a group of 61 women with recurrent major depression, who completed a self-report version of the same instrument, in order to compare treatment outcomes for patients above and below this clinical threshold.Results: Women with high scores (greater than or equal to 35) on the Panic-Agoraphobic Spectrum Self-Report were less likely than women with low scores (
