Nuclear pore complexes. Elimination and reconstruction during mitosis.
Nuclear pore complexes. Elimination and reconstruction during mitosis.
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核孔复合物。有丝分裂过程中的消除和重建。
DOI：
10.1083/jcb.74.2.492
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发表时间：
1977-08
期刊：
影响因子：
--
通讯作者：
Maul GG
中科院分区：
文献类型：
--
作者：
Maul GG
染色体上发现了与核孔复合体相似的核结构。这一发现表明，在没有核膜的情况下，部分毛孔复合体通过有丝分裂被染色体保留。在有丝分裂后的前4小时内，在有无蛋白质合成的情况下，形成了数量大致相同的孔复合体，这证明了孔复合体的重组，而不是新的合成。在没有蛋白质合成的情况下重建的孔隙复合体的结构不能与对照细胞的结构区分开来。
Nuclear structures similar to those of the nuclear pore complex were found on chromosomes. This finding indicates that part of the pore complex is retained by the chromosomes through mitosis in the absence of the nuclear membrane. The formation of approximately the same number of pore complexes in the presence and absence of protein synthesis during the first 4 h after mitosis proves the reassembly rather than new synthesis of the pore complex. The structure of pore complexes reconstructed in the absence of protein synthesis cannot be distinguished from the structure of those of control cells.