IMPLICATIONS OF RNA RNA SPLICING IN EVOLUTION OF EUKARYOTIC CELLS
IMPLICATIONS OF RNA RNA SPLICING IN EVOLUTION OF EUKARYOTIC CELLS
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DOI：
10.1126/science.364651
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发表时间：
1978-01-01
期刊：
影响因子：
56.9
通讯作者：
DARNELL, JE
中科院分区：
文献类型：
--
作者：
DARNELL, JE
真核生物与原核生物相比，mRNA形成的生物化学差异是如此深刻，以至于表明原核生物到真核细胞的连续进化似乎是不可能的。最近在真核生物DNA中发现的编码mRNA的非连续序列可能反映了DNA中信息的古老而非新的分布，并且真核生物独立于原核生物进化。
The differences in the biochemistry of mRNA formation in eukaryotes compared to prokaryotes are so profound as to suggest that sequential prokaryotic to eukaryotic cell evolution seems unlikely. The recently discovered noncontiguous sequences in eukaryotic DNA that encode mRNA may reflect an ancient, rather than a new, distribution of information in DNA and that eukaryotes evolved independently of prokaryotes.