Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure - A randomized, double-blind, placebo-controlled trial
Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure - A randomized, double-blind, placebo-controlled trial
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DOI：
10.1016/j.jacc.2006.11.024
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发表时间：
2007-02-20
影响因子：
24
通讯作者：
McDonald, Ken
中科院分区：
文献类型：
--
作者：
Ponikowski, Piotr;Anker, Stefan D.;McDonald, Ken
目的：本研究旨在探讨促红细胞生成蛋白（ESP）达贝泊汀α是否能改善症状性慢性心力衰竭（CHF）和贫血患者的运动能力。背景：贫血在CHF患者中很常见。方法在一项多中心、随机、双盲、安慰剂对照的研究中，CHF合并贫血(血红蛋白>= 9.0 ~
Objectives This study sought to investigate whether darbepoetin alfa, an erythropoiesis-stimulating protein (ESP), improves exercise capacity in patients with symptomatic chronic heart failure (CHF) and anemia.Background Anemia is common in patients with CHF.Methods In a multicenter, randomized, double-blind, placebo-controlled study, CHF patients with anemia (hemoglobin >= 9.0 to