Immune suppression in the honey bee (Apis mellifera) following infection by Nosema ceranae (Microsporidia)
Immune suppression in the honey bee (Apis mellifera) following infection by Nosema ceranae (Microsporidia)
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DOI：
10.1111/j.1462-2920.2009.01953.x
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发表时间：
2009-09-01
影响因子：
5.1
通讯作者：
Higes, Mariano
中科院分区：
文献类型：
--
作者：
Antunez, Karina;Martin-Hernandez, Raquel;Higes, Mariano
两种微孢子虫感染意大利蜜蜂，即蜜蜂微孢子虫（Nosemaapis）和蜜蜂微孢子虫（Nosemacerebrum）.这项工作提出的证据表明，N。cerebral感染显著抑制蜜蜂的免疫应答，尽管在感染N. apis。免疫抑制也会增加对其他蜜蜂病原体的易感性和衰老。尽管两种微孢子虫在蜜蜂健康中的重要性，但没有关于它们对蜜蜂免疫系统影响的信息，目前的结果可以解释感染蜜蜂的两种小孢子虫之间的不同毒力。
P>Two microsporidia species have been shown to infect Apis mellifera, Nosema apis and Nosema ceranae. This work present evidence that N. ceranae infection significantly suppresses the honey bee immune response, although this effect was not observed following infection with N. apis. Immune suppression would also increase susceptibility to other bee pathogens and senescence. Despite the importance of both Nosema species in honey bee health, there is no information about their effect on the bees' immune system and present results can explain the different virulence between both microsporida infecting honeybees.