Small Intestinal Infections
Small Intestinal Infections
复制标题
小肠感染
DOI：
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发表时间：
2016
影响因子：
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通讯作者：
D. Kotler
中科院分区：
文献类型：
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作者：
K. Munot;D. Kotler
小肠感染在世界范围内极为常见。从病因学来看，它们可能是细菌、病毒或寄生虫。大多数是食源性或水源性的，具体病因因地区而异，病理生理学也不同。非常年轻、非常年老和免疫缺陷的个体最容易因小肠感染而发病或死亡。随着分子诊断测定的发展和早期应用，诊断的复杂性取得了显着的进步，尽管这些测试尚未成为主流。缺乏快速诊断加上小肠感染的自限性，阻碍了口服补液以外的特异性和有效治疗方法的开发。在没有病因诊断的情况下不建议使用抗生素，对于某些感染则根本不建议使用抗生素。
Small intestinal infections are extremely common worldwide. They may be bacterial, viral, or parasitic in etiology. Most are foodborne or waterborne, with specific etiologies differing by region and with diverse pathophysiologies. Very young, very old, and immune-deficient individuals are the most vulnerable to morbidity or mortality from small intestinal infections. There have been significant advances in diagnostic sophistication with the development and early application of molecular diagnostic assays, though these tests have not become mainstream. The lack of rapid diagnoses combined with the self-limited nature of small intestinal infections has hampered the development of specific and effective treatments other than oral rehydration. Antibiotics are not indicated in the absence of an etiologic diagnosis, and not at all in the case of some infections.
影响因子：
11.8
作者：
Patel, Rachna;DuPont, Herbert L.
通讯作者：
DuPont, Herbert L.
影响因子：
7.7
作者：
Checkley, William;Buckley, Gillian;Black, Robert E.
通讯作者：
Black, Robert E.