SUNLAMP-IRRADIATED PHASE-TRANSFER CATALYSIS .1. COBALT CARBONYL CATALYZED SRN1 CARBONYLATIONS OF ARYL AND VINYL HALIDES
SUNLAMP-IRRADIATED PHASE-TRANSFER CATALYSIS .1. COBALT CARBONYL CATALYZED SRN1 CARBONYLATIONS OF ARYL AND VINYL HALIDES
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DOI：
10.1021/jo00156a004
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发表时间：
1983-01-01
影响因子：
3.6
通讯作者：
CAUBERE, P
中科院分区：
文献类型：
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作者：
BRUNET, JJ;SIDOT, C;CAUBERE, P
羰基钴催化的芳基和乙烯基卤化物的羰基化（1大气压）可以在相转移催化条件下容易地实现，条件是反应介质被辐照。照射可以通过商业日光灯来实现。这些反应中的大多数也可以在没有有机溶剂的情况下进行，并且在某些情况下在没有相转移剂的情况下进行。最后，这种新的，廉价的羰基化方法可以非常有效地合成苯并内酰胺和苯并内酯。1首先，它们允许碳-碳键的形成，同时引入官能团。因此，它们可以允许精细分子的功能化。其次，如果反应容易进行，并且所涉及的试剂不是太昂贵，则这些缩合可以用于将廉价的工业材料转化为更高商业价值的衍生物。例如，它们可能在由工业卤化提供的副产物的羰基化中感兴趣。
Cobalt carbonyl catalyzed carbonylation (1 atm) of aryl and vinyl halides may be easily achieved under phase-transfer-catalysis conditions provided that the reaction medium is irradiated. Irradiation may be achieved by a commercial sunlamp. Most of these reactions may also be performed without organic solvent and in some cases without a phase-transfer agent. Finally, this new, inexpensive carbonylation method allows very efficient synthesis of benzolactams and benzolactones.Carbonylations of organic halides constitute interesting reactions from two points of view. 1 First, they allow carbon-carbon bond formation with simultaneous intro-duction of a functional group. Thus, they may allow functionalization of elaborate molecules. Second, if the reactions are easily carried out and the reagents involved are not too expensive, these condensations could be used to transform inexpensive industrial materials to higher commercial value derivatives. For example, they could be of interest in the carbonylation of byproducts provided by industrial halogenations.